CDS
| Accession Number | TCMCG029C39846 |
| gbkey | CDS |
| Protein Id | XP_023743861.1 |
| Location | complement(join(535334..535408,536019..536073,536170..536216,536336..536392,536642..536756,536832..536913,537004..537088,537168..537287,537378..537428,537559..537624,537720..537767,537865..537913,537985..538038,538129..538188,538311..538369,538475..538591,538696..538707)) |
| Gene | LOC111892034 |
| GeneID | 111892034 |
| Organism | Lactuca sativa |
Protein
| Length | 383aa |
| Molecule type | protein |
| Topology | linear |
| Data_file_division | PLN |
| dblink | BioProject:PRJNA432228 |
| db_source | XM_023888093.1 |
| Definition | flap endonuclease 1 isoform X2 [Lactuca sativa] |
EGGNOG-MAPPER Annotation
| COG_category | L |
| Description | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA |
| KEGG_TC | - |
| KEGG_Module | - |
| KEGG_Reaction | - |
| KEGG_rclass | - |
| BRITE |
ko00000
[VIEW IN KEGG] ko00001 [VIEW IN KEGG] ko01000 [VIEW IN KEGG] ko03032 [VIEW IN KEGG] ko03400 [VIEW IN KEGG] ko04147 [VIEW IN KEGG] |
| KEGG_ko |
ko:K04799
[VIEW IN KEGG] |
| EC | - |
| KEGG_Pathway |
ko03030
[VIEW IN KEGG] ko03410 [VIEW IN KEGG] ko03450 [VIEW IN KEGG] map03030 [VIEW IN KEGG] map03410 [VIEW IN KEGG] map03450 [VIEW IN KEGG] |
| GOs | - |
Sequence
| CDS: ATGGGGATAAAGGGTTTAACGAAGCTTCTAGCGGACAATGCCCCGAAGGCCATGAAAGAGCAGAAATTCGAGAGTTATTTTGGTCGGAAAATCGCCATCGATGCTAGCATGAGCATCTACCAGTTTCTGATTGTCGTCGGAAGAAGTGGGACAGAAATGCTGACCAATGAGGCTGGTGATGTGACTAGCCATTTGCAAGGAATGTTCAATCGGACTATTAGGCTTCTGGAATCTGGATTGAAGCCAGTCTATGTTTTTGATGGGGCACCTCCCGATTTGAAGAAACAAGAACTTGCAAAAAGATACTCAAGGCGAGAAGATGCAACAGCAGAGTTAGATGAGGCTATTAAGTCTGGCAATAAGGAAGACATTGAGAAATTTAGTAAACGTACTGTGAAGGTAACAAGACAACACAATGAGGATTGCAAAAAACTTCTAAGGCTTATGGGAGTGCCTGTTATTGAGGCCCCATCTGAAGCAGAGGCACAATGTGCTGCTCTTTGCAAAGCTGATAAGGTGTATGCTGTTGCCTCTGAAGATATGGATTCTCTTACTTTTGGAGCACCAAAATTTCTTAGACATTTAATGGATCCTGCTTCAAGAAAAATTCCCGTGATGGAATTTGATGTTTCCAAGGTTTTAGAGGAACTGAACCTTACAATGGATCAATTTATTGATCTCTGTATCCTATGTGGATGTGATTATTGTGACAGTATTAGAGGTATTGGTGGGCAGACAGCTTTGAAGCTCATTCGTCAACATGGGTCAATAGAAACTATCCTTGAAAATATAAACAAAGAGAGATATCAAATACCTGAGAATTGGCCATATCAGGAGGCTAGACGCCTTTTCAAAGAGCCTTTGGTTTGTGTTGATGATGAACAGCTTGAACTTAAATGGACTTCTCCAGATGAAGAAGGCTTGTTAAACTTCTTGGTGACTGAAAATGGGTTCAACAGTGACAGAGTCACAAAGGCAGTGGAGAAAATAAAAGCTTCCAAGAACAAATCGTCACAAAATCGATTAGAATCATTCTTTAAACCAGTTGTTAGCACTTCTGTTCCCATTAAAAGAAAGGAAACGAATGAAAAAGCTGCAAAAGAACCAGCCAACAAAAAAGCAAAGGGTGGAGCTGGTAGAAAAAAGAAATAG |
| Protein: MGIKGLTKLLADNAPKAMKEQKFESYFGRKIAIDASMSIYQFLIVVGRSGTEMLTNEAGDVTSHLQGMFNRTIRLLESGLKPVYVFDGAPPDLKKQELAKRYSRREDATAELDEAIKSGNKEDIEKFSKRTVKVTRQHNEDCKKLLRLMGVPVIEAPSEAEAQCAALCKADKVYAVASEDMDSLTFGAPKFLRHLMDPASRKIPVMEFDVSKVLEELNLTMDQFIDLCILCGCDYCDSIRGIGGQTALKLIRQHGSIETILENINKERYQIPENWPYQEARRLFKEPLVCVDDEQLELKWTSPDEEGLLNFLVTENGFNSDRVTKAVEKIKASKNKSSQNRLESFFKPVVSTSVPIKRKETNEKAAKEPANKKAKGGAGRKKK |